Rhodium-Catalyzed Enantioselective Cyclization of 2-Allenylbenzoxazoles.
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DOI: 10.1021/acs.orglett.4c00526
Abstract: The enantioselective rhodium-catalyzed cyclization of 2-allenylbenzoxazoles to the corresponding vinyl-functionalized, fused heterocyclic structures is reported. The presented method offers several advantages, including the use of low catalyst loadings, commercially available catalyst precursors, and mild reaction… read more here.
Keywords: catalyzed enantioselective; methodology; cyclization allenylbenzoxazoles; rhodium catalyzed ... See more keywords
Organocatalytic enantioselective (4+3) cyclization for the synthesis of spiro-fused heterocyclic compounds containing isoindolinone, oxepine and indole moieties.
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DOI: 10.1039/d4cc03230f
Abstract: A refined strategy has been developed to control the regioselective asymmetric (4+3) cyclization of α-(3-isoindolinonyl) propargylic alcohols with 2-indolylmethanols, utilizing chiral phosphoric acid catalysis. This innovative organocatalytic cyclization yields spiro isoindolinone-oxepine-fused indoles featuring a spiro-quaternary… read more here.
Keywords: cyclization synthesis; enantioselective cyclization; cyclization; organocatalytic enantioselective ... See more keywords
Non-covalent organocatalyzed enantioselective cyclization reactions of α,β-unsaturated imines
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DOI: 10.3762/bjoc.20.268
Abstract: Asymmetric cycloaddition is a straightforward strategy which enables the synthesis of structurally distinct cyclic derivatives which are difficult to access by other methodologies, using an efficient and atom-economical path from simple precursors. In recent years… read more here.
Keywords: enantioselective cyclization; covalent organocatalyzed; cyclization; cyclization reactions ... See more keywords