Enantioselective 1,3-Dipolar (5+3) Cycloadditions of Oxidopyrylium Ylides and Vinylcyclopropanes toward 9-Oxabicyclononanes.
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DOI: 10.1021/acs.orglett.2c01037
Abstract: We have developed an efficient and mild enantioselective palladium-catalyzed (5+3) cycloaddition of vinylcyclopropanes and oxidopyrylium ylides generated in situ from benzopyranones, in the presence of a chiral PHOX ligand. These reactions afford various highly functionalized… read more here.
Keywords: oxidopyrylium ylides; cycloadditions oxidopyrylium; enantioselective dipolar; vinylcyclopropanes toward ... See more keywords
Enantioselective 1,3-Dipolar Cycloaddition Using (Z)-α-Amidonitroalkenes as a Key Step to the Access to Chiral cis-3,4-Diaminopyrrolidines
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DOI: 10.3390/molecules27144579
Abstract: The enantioselective 1,3-dipolar cycloaddition between imino esters and (Z)-nitroalkenes bearing a masked amino group in the β-position was studied using several chiral ligands and silver salts. The optimized reaction conditions were directly applied to the… read more here.
Keywords: dipolar cycloaddition; amidonitroalkenes key; enantioselective dipolar; using amidonitroalkenes ... See more keywords