Modelling studies of enantioselective extraction of an amino acid derivative in slug flow capillary microreactors
Sign Up to like & getrecommendations! Published in 2018 at "Chemical Engineering Journal"
DOI: 10.1016/j.cej.2018.08.006
Abstract: Abstract This work shows that enantioselective liquid–liquid extraction in microreactors is attractive for chiral separation. A precise control over the residence time in microreactors results in high enantiopurities and low host inventories. Mathematical modelling has… read more here.
Keywords: extraction; amino acid; acid derivative; slug flow ... See more keywords
Highly Enantioselective Extraction of Phenylglycine by a Chiral Macrocyclic Receptor Based on Supramolecular Interactions.
Sign Up to like & getrecommendations! Published in 2020 at "Organic letters"
DOI: 10.1021/acs.orglett.9b04379
Abstract: Using supramolecular interactions, a novel macrocyclic receptor is able to selectively extract zwitterionic phenylglycine from neutral aqueous solutions into chloroform with up to 91.8% ee. Modeling studies, nuclear magnetic resonance experiments, and X-ray diffraction analysis… read more here.
Keywords: macrocyclic receptor; supramolecular interactions; phenylglycine; highly enantioselective ... See more keywords
Enantioselective extraction of unprotected amino acids coupled with racemization
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-020-20402-x
Abstract: Scalable and economical methods for the production of optically pure amino acids, both natural and unnatural, are essential for their use as synthetic building blocks. Currently, enzymatic dynamic kinetic resolution (DKR) underpins some of the… read more here.
Keywords: extraction; amino acids; eecr; coupled racemization ... See more keywords