Regioselective and Enantioselective Intermolecular Buchner Ring Expansions in Flow.
Sign Up to like & getrecommendations! Published in 2017 at "Organic letters"
DOI: 10.1021/acs.orglett.7b02537
Abstract: The first example of a regioselective and enantioselective intermolecular Buchner ring expansion is reported using continuous flow. The practicality and scope of the reaction are greatly improved under flow conditions. Reactions of ethyl diazoacetate with… read more here.
Keywords: enantioselective intermolecular; intermolecular buchner; buchner; regioselective enantioselective ... See more keywords
Enantioselective Intermolecular C–H Amination Directed by a Chiral Cation
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.1c05206
Abstract: The enantioselective amination of C(sp3)–H bonds is a powerful synthetic transformation yet highly challenging to achieve in an intermolecular sense. We have developed a family of anionic variants of the best-in-class catalyst for Rh-catalyzed C–H… read more here.
Keywords: enantioselective intermolecular; cation; intermolecular amination; amination directed ... See more keywords
Rhodium(II)-Catalyzed Enantioselective Intermolecular Aziridination of Alkenes.
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DOI: 10.1021/jacs.2c07337
Abstract: C4-Symmetrical dirhodium(II) tetracarboxylates are highly efficient catalysts for the asymmetric intermolecular aziridination of substituted alkenes with sulfamates. The reaction proceeds with high levels of efficiency and chemoselectivity to afford aziridines with excellent yields of up… read more here.
Keywords: enantioselective intermolecular; aziridination; rhodium catalyzed; aziridination alkenes ... See more keywords
Enantioselective Intermolecular C-O Bond Formation in the Desymmetrization of Diarylmethines Employing a Guanidinylated Peptide-Based Catalyst.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.7b11197
Abstract: We report a series of enantioselective C-O bond cross-coupling reactions based on remote symmetry breaking processes in diarylmethine substrates. The key to the chemistry is multifunctional guanidinylated peptide-based ligands that allow highly selective, intermolecular Cu-catalyzed… read more here.
Keywords: peptide based; enantioselective intermolecular; intermolecular bond; guanidinylated peptide ... See more keywords
Ni-Catalyzed Enantioselective Intermolecular Hydroamination of Branched 1,3-Dienes Using Primary Aliphatic Amines.
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DOI: 10.1021/jacs.9b07253
Abstract: A Ni-catalyzed intermolecular enantioselective hydroamination of branched 1,3-dienes is reported. The method is broadly applicable, highly regio-, chemo- and enantioselective and provides direct access to valuable chiral allylic amines starting from linear or α-branched aliphatic… read more here.
Keywords: enantioselective intermolecular; intermolecular hydroamination; hydroamination branched; branched dienes ... See more keywords
Enantioselective, intermolecular benzylic C-H amination catalysed by an engineered iron-haem enzyme.
Sign Up to like & getrecommendations! Published in 2017 at "Nature chemistry"
DOI: 10.1038/nchem.2783
Abstract: C-H bonds are ubiquitous structural units of organic molecules. Although these bonds are generally considered to be chemically inert, the recent emergence of methods for C-H functionalization promises to transform the way synthetic chemistry is… read more here.
Keywords: enantioselective intermolecular; chemistry; iron haem; amination ... See more keywords
Palladium(II)-catalyzed enantioselective intermolecular oxidative diarylation of internal enamides.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc03202c
Abstract: The construction of vicinal stereogenic centers via the simultaneous formation of two C-C bonds across alkenes under oxidative conditions is a stubborn challenge. Herein, we report a Pd(II)-catalyzed highly enantioselective intermolecular oxidative 1,2-diarylation reaction of… read more here.
Keywords: internal enamides; enantioselective intermolecular; intermolecular oxidative; palladium catalyzed ... See more keywords