Catalytic Enantioselective Intramolecular Oxa-Michael Reaction to α,β-Unsaturated Esters and Amides.
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DOI: 10.1021/jacs.3c03182
Abstract: A bifunctional iminophosphorane (BIMP)-catalyzed, enantioselective intramolecular oxa-Michael reaction of alcohols to tethered, low electrophilicity Michael acceptors is described. Improved reactivity over previous reports (1 day vs 7 days), excellent yields (up to 99%), and enantiomeric… read more here.
Keywords: michael; reaction; michael reaction; oxa michael ... See more keywords
Rh2(ii)-catalyzed enantioselective intramolecular Büchner reaction and aromatic substitution of donor–donor carbenes
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DOI: 10.1039/d1sc05374d
Abstract: The chiral dirhodium(ii) tetracarboxylate-catalyzed enantioselective intramolecular Büchner reaction of donor/donor-carbenes was reported and a series of valuable chiral polycyclic products were synthesized. Both aryloxy enynones and diazo compounds were efficient carbene precursors for this reaction.… read more here.
Keywords: intramolecular chner; donor; chner; enantioselective intramolecular ... See more keywords
Copper-catalyzed Enantioselective Intramolecular Alkylboron Allylic Alkylation
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DOI: 10.1246/cl.180147
Abstract: A reductive C–C-bond-forming cyclization of vinyl-terminated allyl chlorides via alkene hydroboration with 9-BBN-H followed by Cu-catalyzed asymmetric intramolecular allylic alkylation with a new chiral phosphoramidite ligand produced six-membered ring compounds with a tertiary or quaternary… read more here.
Keywords: intramolecular alkylboron; allylic alkylation; enantioselective intramolecular; catalyzed enantioselective ... See more keywords