Synthesis of (+)-Disparlure via Enantioselective Iodolactonization.
Sign Up to like & getrecommendations! Published in 2018 at "Organic letters"
DOI: 10.1021/acs.orglett.7b03911
Abstract: The BINOL-amidine organic catalyst 1 was previously shown to promote highly efficient enantioselective halolactonization reactions of olefinic acids. As part of these studies, it was discovered that the enantioenriched iodolactones could be easily converted into… read more here.
Keywords: synthesis disparlure; disparlure via; disparlure; via enantioselective ... See more keywords
Enantioselective iodolactonization to prepare ε-lactone rings using hypervalent iodine
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DOI: 10.1039/d2sc01587k
Abstract: Despite the rapid growth of enantioselective halolactonization reactions in recent years, most are effective only when forming smaller (6,5,4-membered) rings. Seven-membered ε-lactones, are rarely formed with high selectivity, and never without conformational bias. We describe… read more here.
Keywords: prepare lactone; rings using; enantioselective iodolactonization; using hypervalent ... See more keywords