Enantioselective Isocyanide-based Multicomponent Reaction with Alkylidene Malonates and Phenols.
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DOI: 10.1021/acs.orglett.1c01792
Abstract: A highly enantioselective isocyanide-based multicomponent reaction catalyzed by a chiral N,N'-dioxide/MgII complex was reported. A wide range of substrates were tolerated in this reaction, including alkyl- and aryl-substituted isocyanides with alkylidene malonates and various phenols,… read more here.
Keywords: multicomponent reaction; alkylidene malonates; enantioselective isocyanide; reaction ... See more keywords