Enantioselective Mannich Reaction Employing 1,3,5‐Triaryl‐1,3,5‐triazinanes Catalyzed by Chiral‐at‐Metal Rhodium Complexes
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DOI: 10.1002/ejoc.201700463
Abstract: Chiral-at-metal Rh(III) complexes catalyzed highly efficient enantioselective Mannich reaction of 2-acyl imidazoles with 1,3,5-triazinanes is developed, affording the corresponding adducts in 81-99% yields with up to >99% enantioselectivities. This protocol performs with 0.1 mol %… read more here.
Keywords: chiral metal; enantioselective mannich; mannich reaction; reaction employing ... See more keywords
Development of Catalytic Enantioselective Mannich Reactions Using Esters.
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DOI: 10.1021/acs.orglett.3c04326
Abstract: Catalytic enantioselective Mannich reactions of simple nonactivated esters proceeded using a chiral potassium strong base catalyst prepared from a chiral bisoxazoline and potassium hexamethyldisilazide. Alkyl acetates, alkyl propionates, and an alkyl butyrate were employed as… read more here.
Keywords: enantioselective mannich; catalytic enantioselective; development catalytic; mannich reactions ... See more keywords