Elucidating a Complicated Enantioselective Metabolic Profile: A Study From Rats to Humans Using Optically Pure Doxazosin
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DOI: 10.3389/fphar.2022.834897
Abstract: Doxazosin (DOX) is prescribed as a racemic drug for the clinical treatment of benign prostatic hyperplasia and hypertension. Recent studies found that the two enantiomers of DOX exhibit differences in blood concentration and pharmacological effects.… read more here.
Keywords: metabolites dox; enantioselective metabolic; metabolic; optically pure ... See more keywords