Enantioselective phosphonation of isoquinolines via chiral phosphoric acid-catalyzed dearomatization.
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DOI: 10.1039/d2cc02811e
Abstract: An efficient and enantioselective phosphonation protocol for construction of chiral α-aminophosphates and α-aminodiarylphosphine oxides has been developed based on chiral phosphoric acid-catalyzed dearomatization of isoquinolines. A series of chiral 1,2-dihydroisoquinolines with dimethoxy phosphoryl or diphenylphosphono… read more here.
Keywords: enantioselective phosphonation; chiral phosphoric; phosphoric acid; catalyzed dearomatization ... See more keywords