RNA–protein interactions govern antiviral specificity and encapsidation of broad spectrum anti-HIV reverse transcriptase aptamers
Sign Up to like & getrecommendations! Published in 2017 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkx155
Abstract: Abstract RNA aptamers that bind HIV-1 reverse transcriptase (RT) inhibit HIV-1 replication, but little is known about potential aptamer-specific viral resistance. During replication, RT interacts with diverse nucleic acids. Thus, the genetic threshold for eliciting… read more here.
Keywords: encapsidation; hiv reverse; reverse transcriptase; broad spectrum ... See more keywords
Ascovirus P64 Homologs: A Novel Family of Large Cationic Proteins That Condense Viral Genomic DNA for Encapsidation
Sign Up to like & getrecommendations! Published in 2018 at "Biology"
DOI: 10.3390/biology7030044
Abstract: Eukaryotic dsDNA viruses use small basic protamine-like proteins or histones, typically read more here.
Keywords: novel family; dna; encapsidation; p64 homologs ... See more keywords
Advancing the Rose Rosette Virus Minireplicon and Encapsidation System by Incorporating GFP, Mutations, and the CMV 2b Silencing Suppressor
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v14040836
Abstract: Plant infecting emaraviruses have segmented negative strand RNA genomes and little is known about their infection cycles due to the lack of molecular tools for reverse genetic studies. Therefore, we innovated a rose rosette virus… read more here.
Keywords: rose rosette; encapsidation; replication; rosette virus ... See more keywords