Liposome-encapsulated clodronate specifically depletes spinal microglia and reduces initial neuropathic pain.
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DOI: 10.1016/j.bbrc.2018.03.177
Abstract: Liposome-encapsulated clodronate (LEC) is a specific depletor of macrophages. Our study characterized the LEC depletory effects, given intrathecally, on spinal microglia and assessed its effects on initiation and maintenance of neuropathic pain. Measured by using… read more here.
Keywords: spinal microglia; encapsulated clodronate; neuropathic pain; liposome encapsulated ... See more keywords