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Published in 2020 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-020-04773-1
Abstract: Male BALB/с mice were intravenously infected with Mycobacterium tuberculosis H37Rv (0.5 ml of 2-week culture). One month later, treatment with liposome-encapsulated dextrazide (LEDZ, a conjugate of isonicotinic acid hydrazide (INH) and 40 kDa oxidized dextran…
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Keywords:
structural changes;
encapsulated dextrazide;
changes lungs;
tuberculosis ... See more keywords
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Published in 2021 at "Bulletin of experimental biology and medicine"
DOI: 10.1007/s10517-021-05086-7
Abstract: Administration of the liposome-encapsulated dextrazide (LEDZ) to mice 6 months after infection with mycobacterium BCG vaccine for 3 months modulated metabolism of collagens and the intensity of fibrosis of internal organs. In the liver, we…
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Keywords:
major extracellular;
content major;
encapsulated dextrazide;
content ... See more keywords