Suppression of cerebral ischemia/reperfusion injury by efficient release of encapsulated ifenprodil from liposomes under weakly acidic pH conditions.
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DOI: 10.1016/j.xphs.2019.09.006
Abstract: Although N-methyl-D-aspartate receptors (NMDAR) antagonists are hopeful therapeutic agents against cerebral ischemia/reperfusion (I/R) injury, effective approaches are needed to allow such agents to pass through the blood-brain barrier (BBB), thus increasing bioavailability of the antagonists… read more here.
Keywords: weakly acidic; cerebral ischemia; encapsulated ifenprodil; ischemia reperfusion ... See more keywords