Simultaneous surface display and cargo loading of encapsulin nanocompartments and their use for rational vaccine design.
Sign Up to like & getrecommendations! Published in 2018 at "Vaccine"
DOI: 10.1016/j.vaccine.2018.05.034
Abstract: In the past decades protein nanoparticles have successfully been used for vaccine applications. Their particulate nature and dense repetitive subunit organization makes them perfect carriers for antigen surface display and confers high immunogenicity. Nanoparticles have… read more here.
Keywords: protein; surface; encapsulin; vaccine ... See more keywords
Introduction of Surface Loops as a Tool for Encapsulin Functionalization.
Sign Up to like & getrecommendations! Published in 2021 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.1c01156
Abstract: Encapsulin-based protein cages are nanoparticles with potential biomedical applications, such as targeted drug delivery or imaging. These particles are biocompatible and can be produced in bacteria, allowing large-scale production and protein engineering. In order to… read more here.
Keywords: protein; surface loops; introduction surface; production ... See more keywords
Myxococcus xanthus Encapsulin as a Promising Platform for Intracellular Protein Delivery
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232415591
Abstract: Introducing a new genetically encoded material containing a photoactivatable label as a model cargo protein, based on Myxococcus xanthus (Mx) encapsulin system stably expressed in human 293T cells. Encapsulin from Mx is known to be… read more here.
Keywords: cargo; xanthus encapsulin; platform; encapsulin ... See more keywords