Protecting Encapsulin Nanoparticles with Cysteine-Knot Miniproteins
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.8b00630
Abstract: A big hurdle for the use of protein-based drugs is that they are easily degraded by proteases in the human body. In an attempt to solve this problem, we show the possibility to functionalize TM… read more here.
Keywords: protein; encapsulin nanoparticles; cysteine knot; protecting encapsulin ... See more keywords
Successful PEGylation of hollow encapsulin nanoparticles from Rhodococcus erythropolis N771 without affecting their disassembly and reassembly properties.
Sign Up to like & getrecommendations! Published in 2017 at "Biomaterials science"
DOI: 10.1039/c7bm00207f
Abstract: We developed a hollow PEGylated encapsulin nanoparticle from Rhodococcus erythropolis N771. The hollow engineered encapsulin nanoparticles with His-Tag and Lys residues on the surface were constructed by means of genetic recombination. The Lys residues on… read more here.
Keywords: rhodococcus erythropolis; erythropolis n771; encapsulin nanoparticles; nanoparticle ... See more keywords