A novel NF-κB regulator encoded by circPLCE1 inhibits colorectal carcinoma progression by promoting RPS3 ubiquitin-dependent degradation
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DOI: 10.1186/s12943-021-01404-9
Abstract: Background Constitutive activation of nuclear factor-κB (NF-κB) signaling plays a key role in the development and progression of colorectal carcinoma (CRC). However, the underlying mechanisms of excessive activation of NF-κB signaling remain largely unknown. Methods… read more here.
Keywords: colorectal carcinoma; ubiquitin dependent; rps3; crc ... See more keywords