Y Chromosome Loss and Implications for Oncology
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DOI: 10.1158/1541-7786.mcr-24-0105
Abstract: The Y chromosome has recognized functions in promoting male sex determination and regulating aspects of fertility. However, recent work has demonstrated important roles for the Y chromosome and Y-encoded genes in multiple domains of male… read more here.
Keywords: oncology; encoded genes; cancer; chromosome loss ... See more keywords
Functional Role of Mitochondrial DNA in Cancer Progression
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DOI: 10.3390/ijms23031659
Abstract: Mitochondrial DNA (mtDNA) has been identified as a significant genetic biomarker in disease, cancer and evolution. Mitochondria function as modulators for regulating cellular metabolism. In the clinic, mtDNA variations (mutations/single nucleotide polymorphisms) and dysregulation of… read more here.
Keywords: functional role; encoded genes; role mitochondrial; mitochondrial dna ... See more keywords