Computational exploration of novel antimicrobial modalities targeting fucose-binding lectins and ribosomes in Mycobacterium smegmatis using tRNA-encoded peptides
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2024.2335555
Abstract: Abstract tRNA-Encoded Peptides (tREPs), encoded by small open reading frames (smORFs) within tRNA genes, have recently emerged as a new class of functional peptides exhibiting antiparasitic activity. The discovery of tREPs has led to a… read more here.
Keywords: mycobacterium smegmatis; trna encoded; trna; encoded peptides ... See more keywords
Functions of animal microRNA‐encoded peptides: the race is on!
Sign Up to like & getrecommendations! Published in 2022 at "EMBO reports"
DOI: 10.15252/embr.202254789
Abstract: Short open reading frame (sORF)‐encoded peptides (SEPs) recently emerged as new key players in biology. Pioneering work first established that sORFs encoded by long non‐coding RNAs (lncRNAs) are efficiently translated and produce functional peptides. In… read more here.
Keywords: microrna encoded; functions animal; animal microrna; encoded peptides ... See more keywords
The Essentials on microRNA-Encoded Peptides from Plants to Animals
Sign Up to like & getrecommendations! Published in 2023 at "Biomolecules"
DOI: 10.3390/biom13020206
Abstract: Primary transcripts of microRNAs (pri-miRNAs) were initially defined as long non-coding RNAs that host miRNAs further processed by the microRNA processor complex. A few years ago, however, it was discovered in plants that pri-miRNAs actually… read more here.
Keywords: plants animals; pri mirnas; microrna encoded; essentials microrna ... See more keywords
A Whole New Comprehension about ncRNA-Encoded Peptides/Proteins in Cancers
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14215196
Abstract: Simple Summary The advent of bioinformatics and high-throughput sequencing have disclosed the complexity of ORFs in ncRNAs. Thus, there is a dire need to deep into the real role of ncRNA-encoded proteins/peptides. Considerable progress has… read more here.
Keywords: proteins cancers; peptides proteins; regulation; encoded peptides ... See more keywords
The sORF-Encoded Peptides, ATP Synthase Subunits, Facilitate WSSV Duplication in Shrimp
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v14112449
Abstract: Short open reading frames (sORFs) are a newly identified family of genes, and the functions of most sORF genes and their encoded peptides (SEPs) are still unknown. In this study, two ATP synthase subunits were… read more here.
Keywords: wssv duplication; synthase subunits; atp synthase; mjatp5i mjatp5l ... See more keywords
Functional mechanisms of circular RNA-encoded peptides and future research strategies and directions in nasopharyngeal carcinoma (Review)
Sign Up to like & getrecommendations! Published in 2025 at "International Journal of Oncology"
DOI: 10.3892/ijo.2025.5788
Abstract: Nasopharyngeal carcinoma (NPC) is an epithelial malignancy closely associated with Epstein-Barr virus (EBV) infection. Although patients with early-stage NPC can achieve a high cure rate through radiotherapy, recurrence and distant metastasis remain the primary causes… read more here.
Keywords: encoded peptides; research; nasopharyngeal carcinoma; circular rna ... See more keywords