Genetic encoding of a nonhydrolyzable phosphotyrosine analog in mammalian cells.
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DOI: 10.1039/d2cc01578a
Abstract: Protein tyrosine phosphorylation plays a critical role in signal transduction. We report the genetic incorporation of a phosphotyrosine (pTyr) analog, p-carboxymethyl-L-phenylalanine (CMF), into proteins in mammalian cells. This nonhydrolyzable pTyr analog can facilitate biological studies… read more here.
Keywords: nonhydrolyzable phosphotyrosine; analog; encoding nonhydrolyzable; mammalian cells ... See more keywords