A class I histone deacetylase is implicated in the encystation of Entamoeba invadens.
Sign Up to like & getrecommendations! Published in 2020 at "International journal for parasitology"
DOI: 10.1016/j.ijpara.2020.05.014
Abstract: Epigenetic mechanisms such as histone acetylation and deacetylation participate in regulation of the genes involved in encystation of Entamoeba invadens. However, the histones and target residues involved, and whether the acetylation and deacetylation of the… read more here.
Keywords: encystation entamoeba; class histone; histone deacetylase; entamoeba invadens ... See more keywords
Antiproliferation and Antiencystation Effect of Class II Histone Deacetylase Inhibitors on Acanthamoeba castellanii.
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DOI: 10.1021/acsinfecdis.1c00390
Abstract: Acanthamoeba is a ubiquitous and free-living protozoan pathogen responsible for causing Acanthamoeba keratitis (AK), a severe corneal infection inflicting immense pain that can result in permanent blindness. A drug-based treatment of AK has remained arduous… read more here.
Keywords: encystation; deacetylase inhibitors; histone deacetylase; hdaci ... See more keywords
A cell-cycle–dependent GARP-like transcriptional repressor regulates the initiation of differentiation in Giardia lamblia
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DOI: 10.1101/2021.05.27.446072
Abstract: Transcriptional regulation of differentiation is critical for parasitic pathogens to adapt to environmental changes and regulate transmission. In response to encystation stimuli, Giardia lamblia cells shift from G1+S phase of the cell cycle to G2+M.… read more here.
Keywords: cycle; repressor; cell cycle; differentiation ... See more keywords
Morphological and Motility Features of the Stable Bleb-Driven Monopodial Form of Entamoeba and Its Importance in Encystation
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DOI: 10.1128/iai.00903-19
Abstract: Entamoeba histolytica and its reptilian counterpart and encystation model Entamoeba invadens formed a polarized monopodial morphology when treated with pentoxifylline. This morphology was propelled by retrograde flow of the cell surface resulting from a cyclic… read more here.
Keywords: form; encystation; motility; stable bleb ... See more keywords