Bacterial colonization in the apical part of extracted human teeth following root-end resection and filling: a confocal laser scanning microscopy study
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Oral Investigations"
DOI: 10.1007/s00784-017-2107-1
Abstract: ObjectivesThe purpose of this study was to evaluate Enterococcus faecalis colonization at the apical part of root canals following root-end resection and filling using confocal laser scanning microscopy (CLSM).Materials and methodsThe apical 3-mm root-ends of… read more here.
Keywords: resection filling; microscopy; end resection; following root ... See more keywords
SAMHD1 Promotes DNA End Resection to Facilitate DNA Repair by Homologous Recombination.
Sign Up to like & getrecommendations! Published in 2017 at "Cell reports"
DOI: 10.1016/j.celrep.2017.08.008
Abstract: DNA double-strand break (DSB) repair by homologous recombination (HR) is initiated by CtIP/MRN-mediated DNA end resection to maintain genome integrity. SAMHD1 is a dNTP triphosphohydrolase, which restricts HIV-1 infection, and mutations are associated with Aicardi-Goutières… read more here.
Keywords: end resection; dna end; repair; samhd1 ... See more keywords
Control of DNA end resection by yeast Hmo1p affects efficiency of DNA end-joining.
Sign Up to like & getrecommendations! Published in 2017 at "DNA repair"
DOI: 10.1016/j.dnarep.2017.03.002
Abstract: The primary pathways for DNA double strand break (DSB) repair are homologous recombination (HR) and non-homologous end-joining (NHEJ). The choice between HR and NHEJ is influenced by the extent of DNA end resection, as extensive… read more here.
Keywords: end joining; end resection; end; dna end ... See more keywords
ZGRF1 promotes end resection of DNA homologous recombination via forming complex with BRCA1/EXO1
Sign Up to like & getrecommendations! Published in 2021 at "Cell Death Discovery"
DOI: 10.1038/s41420-021-00633-7
Abstract: To maintain genomic stability, the mammalian cells has evolved a coordinated response to DNA damage, including activation of DNA repair and cell cycle checkpoint processes. Exonuclease 1 (EXO1)-dependent excision of DNA ends is important for… read more here.
Keywords: zgrf1; dna; end resection; homologous recombination ... See more keywords
Regulatory control of DNA end resection by Sae2 phosphorylation
Sign Up to like & getrecommendations! Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-06417-5
Abstract: DNA end resection plays a critical function in DNA double-strand break repair pathway choice. Resected DNA ends are refractory to end-joining mechanisms and are instead channeled to homology-directed repair. Using biochemical, genetic, and imaging methods,… read more here.
Keywords: sae2; end resection; end; dna end ... See more keywords
Homologous recombination suppresses transgenerational DNA end resection and chromosomal instability in fission yeast
Sign Up to like & getrecommendations! Published in 2023 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkad160
Abstract: Abstract Chromosomal instability (CIN) drives cell-to-cell heterogeneity, and the development of genetic diseases, including cancer. Impaired homologous recombination (HR) has been implicated as a major driver of CIN, however, the underlying mechanism remains unclear. Using… read more here.
Keywords: end resection; fission yeast; end; chromosomal instability ... See more keywords
MSH2-MSH3 promotes DNA end resection during homologous recombination and blocks polymerase theta-mediated end-joining through interaction with SMARCAD1 and EXO1.
Sign Up to like & getrecommendations! Published in 2023 at "Nucleic acids research"
DOI: 10.1093/nar/gkad308
Abstract: DNA double-strand break (DSB) repair via homologous recombination is initiated by end resection. The extent of DNA end resection determines the choice of the DSB repair pathway. Nucleases for end resection have been extensively studied.… read more here.
Keywords: end resection; msh2 msh3; resection; end ... See more keywords
Recruitment of Scc2/4 to double-strand breaks depends on γH2A and DNA end resection
Sign Up to like & getrecommendations! Published in 2022 at "Life Science Alliance"
DOI: 10.26508/lsa.202101244
Abstract: DSB recruitment of the cohesin loader Scc2/4 relies on Tel1 and γH2A, but contrary to cohesin not on Mec1; binding emanates from the break site and depends on as well as coincides with end resection. read more here.
Keywords: recruitment scc2; recruitment; end resection;