Articles with "end tethering" as a keyword



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Structurally distinct Mre11 domains mediate MRX functions in resection, end-tethering and DNA damage resistance

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Published in 2018 at "Nucleic Acids Research"

DOI: 10.1093/nar/gky086

Abstract: Abstract Sae2 cooperates with the Mre11–Rad50-Xrs2 (MRX) complex to initiate resection of DNA double-strand breaks (DSBs) and to maintain the DSB ends in close proximity to allow their repair. How these diverse MRX-Sae2 functions contribute… read more here.

Keywords: dna damage; sae2; end tethering; resistance ... See more keywords