Extracellular vesicles derived from endometrial human mesenchymal stem cells enhance embryo yield and quality in an aged murine model†.
Sign Up to like & getrecommendations! Published in 2019 at "Biology of reproduction"
DOI: 10.1093/biolre/ioy263
Abstract: Advanced age is a risk factor undermining women's fertility. Hence, the optimization of assisted reproduction techniques is an interdisciplinary challenge that requires the improvement of in vitro culture systems. Here, we hypothesize that supplementation of… read more here.
Keywords: extracellular vesicles; endmscs; murine model; aged murine ... See more keywords
Murine embryos exposed to human endometrial MSCs-derived extracellular vesicles exhibit higher VEGF/PDGF AA release, increased blastomere count and hatching rates
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0196080
Abstract: Endometrial Mesenchymal Stromal Cells (endMSCs) are multipotent cells with immunomodulatory and pro-regenerative activity which is mainly mediated by a paracrine effect. The exosomes released by MSCs have become a promising therapeutic tool for the treatment… read more here.
Keywords: extracellular vesicles; embryos; endmscs; vegf pdgf ... See more keywords