Alternative Splicing in the Nuclear Receptor Superfamily Expands Gene Function to Refine Endo-Xenobiotic Metabolism
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DOI: 10.1124/dmd.119.089102
Abstract: The human genome encodes 48 nuclear receptor (NR) genes, whose translated products transform chemical signals from endo-xenobiotics into pleotropic RNA transcriptional profiles that refine drug metabolism. This review describes the remarkable diversification of the 48… read more here.
Keywords: methodology; metabolism; cassette; endo xenobiotic ... See more keywords