Can We Re-Engineer the Endocrine Pancreas?
Sign Up to like & getrecommendations! Published in 2018 at "Current Diabetes Reports"
DOI: 10.1007/s11892-018-1072-7
Abstract: Purpose of ReviewEngineering endocrine pancreatic tissue is an emerging topic in type 1 diabetes with the intent to overcome the current limitation of β cell transplantation. During islet isolation, the vascularized structure and surrounding extracellular… read more here.
Keywords: endocrine pancreas; ecm; engineer endocrine; tissue ... See more keywords
Interaction of Exocrine and Endocrine Pancreas in Obesity Ciliopathies
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DOI: 10.2337/db18-54-or
Abstract: Ciliopathies are rare genetic disorders characterized by dysfunction in primary cilia. Two ciliopathies, Alstrom Syndrome and Bardet-Biedl Syndrome (BBS), are characterized by high rates of obesity. However, they have strikingly different rates of diabetes. The… read more here.
Keywords: endocrine pancreas; interaction exocrine; exocrine pancreas; pancreas enzymes ... See more keywords
The endocrine pancreas during exercise in people with and without type 1 diabetes: Beyond the beta-cell
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.981723
Abstract: Although important for digestion and metabolism in repose, the healthy endocrine pancreas also plays a key role in facilitating energy transduction around physical exercise. During exercise, decrements in pancreatic β-cell mediated insulin release opposed by… read more here.
Keywords: cell; endocrine pancreas; exercise people; type diabetes ... See more keywords
Bioengineering the Vascularized Endocrine Pancreas: A Fine-Tuned Interplay Between Vascularization, Extracellular-Matrix-Based Scaffold Architecture, and Insulin-Producing Cells
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DOI: 10.3389/ti.2022.10555
Abstract: Intrahepatic islet transplantation is a promising β-cell replacement strategy for the treatment of type 1 diabetes. Instant blood-mediated inflammatory reactions, acute inflammatory storm, and graft revascularization delay limit islet engraftment in the peri-transplant phase, hampering… read more here.
Keywords: vascularized endocrine; endocrine pancreas; function; vascularization ... See more keywords
Fetal Programming of the Endocrine Pancreas: Impact of a Maternal Low-Protein Diet on Gene Expression in the Perinatal Rat Pancreas
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DOI: 10.3390/ijms231911057
Abstract: In rats, the time of birth is characterized by a transient rise in beta cell replication, as well as beta cell neogenesis and the functional maturation of the endocrine pancreas. However, the knowledge of the… read more here.
Keywords: endocrine pancreas; rat pancreas; expression; protein diet ... See more keywords