Cadmium in vivo exposure alters stress response and endocrine-related genes in the freshwater snail Physa acuta. New biomarker genes in a new model organism.
Sign Up to like & getrecommendations! Published in 2017 at "Environmental pollution"
DOI: 10.1016/j.envpol.2016.10.012
Abstract: The freshwater snail Physa acuta is a sensitive organism to xenobiotics that is appropriate for toxicity testing. Cadmium (Cd) is a heavy metal with known toxic effects on several organisms, which include endocrine disruption and… read more here.
Keywords: freshwater snail; response; snail physa; stress response ... See more keywords
A comprehensive review of regulatory test methods for endocrine adverse health effects
Sign Up to like & getrecommendations! Published in 2017 at "Critical Reviews in Toxicology"
DOI: 10.1080/10408444.2016.1272095
Abstract: Abstract Development of new endocrine disruption-relevant test methods has been the subject of intensive research efforts for the past several decades, prompted in part by mandates in the 1996 Food Quality Protection Act (FQPA). While… read more here.
Keywords: adverse health; endocrine related; test methods; test ... See more keywords
OR23-2 Increased Exposure to Brominated Flame Retardant Associates with Differences in DNA Methylation Similar to Natural Estrogen
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the Endocrine Society"
DOI: 10.1210/js.2019-or23-2
Abstract: Abstract In 1973, approximately 6.5 million Michigan residents were exposed to an industrial mixture of polybrominated biphenyl (PBB), an endocrine-disrupting compound, when it was added to farm animal feed during a factory accident. Highly exposed… read more here.
Keywords: endocrine; endocrine related; estrogen; cpgs ... See more keywords
Endocrine-related adverse conditions in patients receiving immune checkpoint inhibition: an ESE clinical practice guideline
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Endocrinology"
DOI: 10.1530/eje-22-0689
Abstract: Immune checkpoint inhibitors (ICI) have revolutionized cancer treatment but are associated with significant autoimmune endocrinopathies that pose both diagnostic and treatment challenges. The aim of this guideline is to provide clinicians with the best possible… read more here.
Keywords: treatment; related adverse; endocrine related; immune checkpoint ... See more keywords
Targeting mitotic pathways for endocrine-related cancer therapeutics.
Sign Up to like & getrecommendations! Published in 2017 at "Endocrine-related cancer"
DOI: 10.1530/erc-17-0080
Abstract: A colossal amount of basic research over the past few decades has provided unprecedented insights into the highly complex process of cell division. There is an ever-expanding catalog of proteins that orchestrate, participate and coordinate… read more here.
Keywords: pathways endocrine; related cancer; targeting mitotic; mitotic pathways ... See more keywords
Non-coding RNAs: long non-coding RNAs and microRNAs in endocrine-related cancers.
Sign Up to like & getrecommendations! Published in 2018 at "Endocrine-related cancer"
DOI: 10.1530/erc-17-0548
Abstract: The human genome is 'pervasively transcribed' leading to a complex array of non-coding RNAs (ncRNAs) that far outnumber coding mRNAs. ncRNAs have regulatory roles in transcription and post-transcriptional processes as well numerous cellular functions that… read more here.
Keywords: coding rnas; rnas long; long non; non coding ... See more keywords
Role of circadian rhythm disorders in EMT and tumor-immune interactions in endocrine-related cancers.
Sign Up to like & getrecommendations! Published in 2021 at "Endocrine-related cancer"
DOI: 10.1530/erc-20-0390
Abstract: The circadian rhythm is a major environmental regulator of plants and animal physiology. The alternation of days and nights is translated at the cell and tissue level thanks to a molecular machinery, called the circadian… read more here.
Keywords: rhythm disorders; role circadian; endocrine related; related cancers ... See more keywords
Mechanisms of Cell Adhesion Molecules in Endocrine-Related Cancers: A Concise Outlook
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.865436
Abstract: Chemotherapy is a critical treatment for endocrine-related cancers; however, chemoresistance and disease recurrence remain a challenge. The interplay between cancer cells and the tumor microenvironment via cell adhesion molecules (CAMs) promotes drug resistance, known as… read more here.
Keywords: cell adhesion; adhesion; adhesion molecules; endocrine related ... See more keywords