Neoadjuvant Chemotherapy or Endocrine Therapy for Invasive Ductal Carcinoma of the Breast With High Hormone Receptor Positivity and Human Epidermal Growth Factor Receptor 2 Negativity
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DOI: 10.1001/jamanetworkopen.2021.1785
Abstract: Key Points Question Is neoadjuvant endocrine therapy (NET) an alternative treatment for neoadjuvant chemotherapy (NACT) in patients with invasive ductal carcinoma (IDC) of the breast who have strong hormone receptor (HR) positivity and human epidermal… read more here.
Keywords: endocrine therapy; hormone receptor; invasive ductal; ductal carcinoma ... See more keywords
Association of Endocrine Therapy Initiation Timeliness With Adherence and Continuation in Low-Income Women With Breast Cancer
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DOI: 10.1001/jamanetworkopen.2022.25345
Abstract: Key Points Question How are adjuvant endocrine therapy initiation timelines associated with adherence and continuation of treatment in low-income women with breast cancer? Findings In this cohort study of 1711 women with breast cancer enrolled… read more here.
Keywords: endocrine therapy; breast cancer; women breast; initiation ... See more keywords
Association of Endocrine Therapy for HR+/ERBB2+ Metastatic Breast Cancer With Survival Outcomes
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DOI: 10.1001/jamanetworkopen.2022.47154
Abstract: This cohort study investigates the association of hormone receptor status and first-line endocrine therapy with survival among patients with hormone receptor–positive (HR+) and human epidermal growth factor receptor 2–positive (ERBB2+ metastatic breast cancer. read more here.
Keywords: erbb2 metastatic; survival; breast cancer; metastatic breast ... See more keywords
Ribosome biogenesis‐based predictive biomarkers in endocrine therapy (Anastrozole) combined with mTOR inhibitor (Vistusertib) in endometrial cancer: translational study from the VICTORIA trial in collaboration with the GINECO group
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13340
Abstract: Resistance of advanced hormone‐dependent endometrial carcinoma to endocrine therapy remains a worldwide clinical issue. We recently reported that the combination of Vistusertib (V, mTOR inhibitor) and Anastrozole (A, aromatase inhibitor) improves the progression‐free rate compared… read more here.
Keywords: ribosome biogenesis; mtor inhibitor; inhibitor; endocrine therapy ... See more keywords
The cognitive effects of endocrine therapy in survivors of breast cancer: A prospective longitudinal study up to 6 years after treatment
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DOI: 10.1002/cncr.31858
Abstract: After treatment of primary breast cancer, endocrine therapy (ET) is prescribed for patients with hormone receptor–positive cancers. Despite ET recommendations of 5 to 10 years of treatment, to the authors’ knowledge there is little prospective… read more here.
Keywords: endocrine therapy; treatment; study; breast cancer ... See more keywords
The association of pharmacy fill synchronization with breast cancer endocrine therapy adherence
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DOI: 10.1002/cncr.32433
Abstract: One‐third to one‐half of patients prescribed adjuvant endocrine therapy are nonadherent during the recommended 5‐year endocrine therapy course. This study investigated whether poor pharmacy synchronization of medication fills (requiring refills on different days) acts as… read more here.
Keywords: endocrine therapy; endocrine; pharmacy; synchronization ... See more keywords
Impact of adjuvant endocrine therapy in older patients with comorbidities and estrogen receptor‐positive, node‐negative breast cancer—A National Cancer Database analysis
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DOI: 10.1002/cncr.33489
Abstract: Data are lacking about the benefit of adjuvant endocrine therapy (ET) in older patients with multiple comorbidities. The authors sought to determine the effect of ET on the survival of older patients who had multiple… read more here.
Keywords: endocrine therapy; adjuvant endocrine; therapy older; receptor ... See more keywords
De‐escalation of five‐year adjuvant endocrine therapy in patients with estrogen receptor‐low positive (immunohistochemistry staining 1%‐10%) breast cancer: Propensity‐matched analysis from a prospectively maintained cohort
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DOI: 10.1002/cncr.34155
Abstract: The standard 5 years of endocrine therapy has demonstrated additional benefits compared with short‐term (2‐3 years) treatment in patients with estrogen receptor (ER)‐positive breast cancer; however, data specific to ER‐low positive breast cancer (1%‐10% by… read more here.
Keywords: estrogen receptor; breast cancer; patients estrogen; endocrine therapy ... See more keywords
Adjuvant Endocrine Therapy.
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DOI: 10.1007/978-3-319-70197-4_2
Abstract: The use of hormonal therapy in breast cancer has improved the overall outcome for patients with early-stage hormone receptor-positive disease. The choice of hormone therapy is related to multiple factors, including menopausal state, patient preference,… read more here.
Keywords: adjuvant endocrine; hormone; endocrine therapy; cancer ... See more keywords
Provider perspectives on barriers and facilitators to adjuvant endocrine therapy-related symptom management
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DOI: 10.1007/s00520-017-3799-0
Abstract: PurposeAdjuvant endocrine therapy (AET) utilization is linked to improved clinical outcomes among breast cancer survivors (BCS); yet, AET adherence rates remain suboptimal. Little is known about provider perspectives regarding barriers and facilitators to AET-related symptom… read more here.
Keywords: endocrine therapy; aet related; provider; level ... See more keywords
Sexual quality of life assessment in young women with breast cancer during adjuvant endocrine therapy and patient-reported supportive measures
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DOI: 10.1007/s00520-022-06810-3
Abstract: Sexual quality of life (QoL) is affected during and after breast cancer (BC) treatment. The purpose was to investigate sexual and global QoL and patient-reported measures to address this issue in young women ( read more here.
Keywords: cancer; endocrine therapy; patient reported; supportive measures ... See more keywords