Preformed Ω-profile closure and kiss-and-run mediate endocytosis and diverse endocytic modes in neuroendocrine chromaffin cells
Sign Up to like & getrecommendations! Published in 2021 at "Neuron"
DOI: 10.1016/j.neuron.2021.07.019
Abstract: Transformation of flat membrane into round vesicles is generally thought to underlie endocytosis and produce speed-, amount-, and vesicle-size-specific endocytic modes. Visualizing depolarization-induced exocytic and endocytic membrane transformation in live neuroendocrine chromaffin cells, we found… read more here.
Keywords: neuroendocrine chromaffin; endocytic modes; chromaffin cells; transformation ... See more keywords
Discrete GPCR-triggered endocytic modes enable β-arrestins to flexibly regulate cell signaling
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.1101/2022.07.13.499995
Abstract: β-arrestins are master regulators of cellular signaling that operate by desensitizing ligand-activated G protein-coupled receptors (GPCRs) at the plasma membrane and promoting their subsequent endocytosis. The endocytic activity of β-arrestins is ligand-dependent, triggered by GPCR… read more here.
Keywords: triggered endocytic; gpcr triggered; endocytic modes; cell signaling ... See more keywords