Role of Endocytosis in Nanoparticle Penetration of 3D Pancreatic Cancer Spheroids.
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DOI: 10.1021/acs.molpharmaceut.8b01078
Abstract: Robust deposition of extracellular matrix is a significant barrier for delivery of nanotherapeutics and small-molecule anticancer drugs to different tumors including pancreatic ductal adenocarcinoma. Here, we investigated permeation and total uptake of polystyrene nanoparticles of… read more here.
Keywords: 100 500; penetration; nanoparticle; pancreatic cancer ... See more keywords