Endocytic proteins mediating GPR15 receptor internalisation provide insight into the underlying mechanisms.
Sign Up to like & getrecommendations! Published in 2023 at "FEBS letters"
DOI: 10.1002/1873-3468.14622
Abstract: GPR15 is a G protein-coupled receptor involved in immune disorders such as human immunodeficiency virus-induced enteropathy, multiple sclerosis, and colitis. Yet, the important endocytosis mechanism of GPR15 remained unclear. This study determined the participation of… read more here.
Keywords: gpr15; proteins mediating; endocytic proteins; internalisation ... See more keywords
Condensation of Ede1 promotes the initiation of endocytosis
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DOI: 10.7554/elife.72865
Abstract: Clathrin-mediated endocytosis is initiated by a network of weakly interacting proteins through a poorly understood mechanism. Ede1, the yeast homolog of mammalian Eps15, is an early-arriving endocytic protein and a key initiation factor. In the… read more here.
Keywords: endocytic proteins; initiation endocytosis; region; endocytosis ... See more keywords