Rapid and facile quantitation of polyplex endocytic trafficking
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Controlled Release"
DOI: 10.1016/j.jconrel.2016.12.035
Abstract: ABSTRACT Design of safe and effective synthetic nucleic acid delivery vectors such as polycation/DNA or polycation/siRNA complexes (polyplexes) will be facilitated by quantitative understanding of the mechanisms by which such materials escort cargo from the… read more here.
Keywords: subcellular fractionation; endocytic trafficking; trafficking; microscopy ... See more keywords
A Targeted RNAi Screen Identifies Endocytic Trafficking Factors That Control GLP-1 Receptor Signaling in Pancreatic β-Cells
Sign Up to like & getrecommendations! Published in 2017 at "Diabetes"
DOI: 10.2337/db17-0639
Abstract: The glucagon-like peptide 1 (GLP-1) receptor (GLP-1R) is a key target for type 2 diabetes (T2D) treatment. Because endocytic trafficking of agonist-bound receptors is one of the most important routes for regulation of receptor signaling,… read more here.
Keywords: endocytic trafficking; glp; pancreatic cells; receptor signaling ... See more keywords
Membrane Heterogeneity Controls Cellular Endocytic Trafficking
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DOI: 10.3389/fcell.2020.00757
Abstract: Endocytic trafficking relies on highly localized events in cell membranes. Endocytosis involves the gathering of protein (cargo/receptor) at distinct plasma membrane locations defined by specific lipid and protein compositions. Simultaneously, the molecular machinery that drives… read more here.
Keywords: endocytic trafficking; membrane heterogeneity; heterogeneity controls; membrane ... See more keywords
Endocytic trafficking induces lateral root founder cell specification in Arabidopsis thaliana in a process distinct from the auxin-induced pathway
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.1060021
Abstract: Plants can modify their body structure, such as their root architecture, post-embryonically. For example, Arabidopsis thaliana can develop lateral roots as part of an endogenous program or in response to biotic and abiotic stimuli. Root… read more here.
Keywords: root; endocytic trafficking; root founder; lateral root ... See more keywords