Articles with "endogenous agonist" as a keyword



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N-arachidonoyl glycine, another endogenous agonist of GPR55.

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Published in 2017 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2017.07.038

Abstract: Interest in lipoamino acids as endogenous modulators of G-protein coupled receptors has escalated due to their involvement in a variety of physiologic processes. In particular, a role for these amino acid conjugates has emerged in… read more here.

Keywords: gpr55; another endogenous; endogenous agonist; agonist gpr55 ... See more keywords
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Crystal structure of the endogenous agonist-bound prostanoid receptor EP3

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Published in 2018 at "Nature Chemical Biology"

DOI: 10.1038/s41589-018-0171-8

Abstract: Prostanoids are a series of bioactive lipid metabolites that function in an autacoid manner via activation of cognate G-protein-coupled receptors (GPCRs). Here, we report the crystal structure of human prostaglandin (PG) E receptor subtype EP3… read more here.

Keywords: prostanoid receptor; crystal structure; receptor ep3; endogenous agonist ... See more keywords