Fc-binding antibody-recruiting molecules exploit endogenous antibodies for anti-tumor immune responsesâ€
Sign Up to like & getrecommendations! Published in 2020 at "Chemical Science"
DOI: 10.1039/d0sc00017e
Abstract: Redirecting endogenous antibodies in the bloodstream to tumor cells using synthetic molecules is a promising approach to trigger anti-tumor immune responses. However, current molecular designs only enable the use of a small fraction of endogenous… read more here.
Keywords: binding antibody; immune responses; endogenous antibodies; anti tumor ... See more keywords
A perspective toward mass spectrometry-based de novo sequencing of endogenous antibodies
Sign Up to like & getrecommendations! Published in 2022 at "mAbs"
DOI: 10.1080/19420862.2022.2079449
Abstract: ABSTRACT A key step in therapeutic and endogenous humoral antibody characterization is identifying the amino acid sequence. So far, this task has been mainly tackled through sequencing of B-cell receptor (BCR) repertoires at the nucleotide… read more here.
Keywords: mass spectrometry; endogenous antibodies; perspective toward; toward mass ... See more keywords