Identification of Endogenous Biomarkers to Predict the Propensity of Drug Candidates to Cause Hepatic or Renal Transporter-Mediated Drug-Drug Interactions.
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DOI: 10.1016/j.xphs.2017.04.007
Abstract: Drug transporters expressed in liver and kidney play a critical role in the elimination of a wide range of drugs and xenobiotics and inhibition of these transporters may therefore cause clinically significant drug-drug interactions (DDIs).… read more here.
Keywords: endogenous biomarkers; drug interactions; drug candidates; drug ... See more keywords