Endogenous circadian reporters reveal functional differences of PERIOD paralogs and the significance of PERIOD:CK1 stable interaction
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2212255120
Abstract: Significance Genetic and environmental disruption to the circadian clock can lead to diverse diseases including sleep and metabolic disorders. Cells with engineered circadian reporters, especially bioluminescence reporters, have been instrumental in understanding the mechanisms underpinning… read more here.
Keywords: endogenous circadian; period; reporters reveal; circadian reporters ... See more keywords
Effects of obstructive sleep apnea on endogenous circadian rhythms assessed during relaxed wakefulness; an exploratory analysis
Sign Up to like & getrecommendations! Published in 2020 at "Chronobiology International"
DOI: 10.1080/07420528.2020.1740723
Abstract: ABSTRACT Obstructive sleep apnea (OSA) is associated with hypertension, cardiovascular disease, and a change in the 24 h pattern of adverse cardiovascular events and mortality. Adverse cardiovascular events occur more frequently in the middle of… read more here.
Keywords: circadian rhythms; exploratory analysis; apnea; endogenous circadian ... See more keywords
Endogenous circadian time genes expressions in the liver of mice under constant darkness
Sign Up to like & getrecommendations! Published in 2020 at "BMC Genomics"
DOI: 10.1186/s12864-020-6639-4
Abstract: Background The circadian rhythms regulate physiological functions and metabolism. Circadian Time (CT) is a unit to quantify the rhythm of endogenous circadian clock, independent of light influence. To understand the gene expression changes throughout CT,… read more here.
Keywords: endogenous circadian; oscillation; constant darkness; circadian time ... See more keywords