SAT0058 DEFICIENT DNA DAMAGE RESPONSE AND REPAIR IN ACTIVE RHEUMATOID ARTHRITIS AND THE EFFECT OF TREATMENT
Sign Up to like & getrecommendations! Published in 2019 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2019-eular.5129
Abstract: Background: Increased endogenous DNA damage poses a serious threat to cell health, since it may lead to mutagenesis, genomic instability and cellular apoptosis. DNA damage accumulation in immune cells occurs in patients with chronic inflammatory… read more here.
Keywords: dna damage; endogenous dna; dna; treatment ... See more keywords
Cytosolic DNA sensors and glial responses to endogenous DNA
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1130172
Abstract: Genomic instability is a key driving force for the development and progression of many neurodegenerative diseases and central nervous system (CNS) cancers. The initiation of DNA damage responses is a critical step in maintaining genomic… read more here.
Keywords: endogenous dna; dna; sensors glial; dna sensors ... See more keywords
Are Changes in the Percentage of Specific Leukocyte Subpopulations Associated with Endogenous DNA Damage Levels in Testicular Cancer Patients?
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22158281
Abstract: Chemoresistance of germ cell tumors (GCTs) represents an intensively studied property of GCTs that is the result of a complicated multifactorial process. One of the driving factors in this process is the tumor microenvironment (TME).… read more here.
Keywords: dna damage; endogenous dna; gct patients; damage ... See more keywords