Impaired endogenous fibrinolysis at high shear using a point-of-care test in STEMI is associated with alterations in clot architecture
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DOI: 10.1007/s11239-018-01799-1
Abstract: Impaired endogenous fibrinolysis is an adverse prognostic biomarker in acute coronary syndrome (ACS). Abnormally dense in vitro fibrin thrombi have been demonstrated in ACS patients and related to hypofibrinolysis using cumbersome, laboratory-based methods. We aimed… read more here.
Keywords: point care; clot architecture; endogenous fibrinolysis; fibrinolysis ... See more keywords
Rationale and design of “Can Very Low Dose Rivaroxaban (VLDR) in addition to dual antiplatelet therapy improve thrombotic status in acute coronary syndrome (VaLiDate-R)” study
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DOI: 10.1007/s11239-019-02014-5
Abstract: Impaired endogenous fibrinolysis is novel biomarker that can identify patients with ACS at increased cardiovascular risk. The addition of Very Low Dose Rivaroxaban (VLDR) to dual antiplatelet therapy has been shown to reduce cardiovascular events… read more here.
Keywords: status; vldr; low dose; addition ... See more keywords
Impaired endogenous fibrinolysis in ST-segment elevation myocardial infarction patients undergoing primary percutaneous coronary intervention is a predictor of recurrent cardiovascular events: the RISK PPCI study
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DOI: 10.1093/eurheartj/ehy656
Abstract: Aims The endogenous fibrinolytic system serves to prevent lasting thrombotic occlusion and infarction following initiation of coronary thrombosis. We aimed to determine whether impaired endogenous fibrinolysis can identify patients with ST-segment elevation myocardial infarction (STEMI)… read more here.
Keywords: risk; segment; myocardial infarction; endogenous fibrinolysis ... See more keywords
P4744Patients with atrial fibrillation exhibit a systemic prothrombotic state attributable to impaired endogenous fibrinolysis
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DOI: 10.1093/eurheartj/ehz745.1120
Abstract: The association of atrial fibrillation (AF) with thromboembolic stroke due to stasis in the left atrium and left atrial appendage is well described. Whether AF is associated with a systemic prothrombotic state, detectable in peripheral… read more here.
Keywords: atrial fibrillation; blood; prothrombotic state; endogenous fibrinolysis ... See more keywords
Apixaban enhances endogenous fibrinolysis in patients with atrial fibrillation
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DOI: 10.1093/europace/euz176
Abstract: Abstract Aims Approximately 20% of ischaemic stroke patients exhibit spontaneous arterial recanalization, attributable to endogenous fibrinolysis, which strongly relates to improved functional outcome. The impact of oral anticoagulants on endogenous fibrinolysis is unknown. Our aim… read more here.
Keywords: atrial fibrillation; fibrinolysis; apixaban enhances; endogenous fibrinolysis ... See more keywords