Metformin increases fasting glucose clearance and endogenous glucose production in non-diabetic individuals
Sign Up to like & getrecommendations! Published in 2019 at "Diabetologia"
DOI: 10.1007/s00125-019-05042-1
Abstract: To the Editor: It is currently accepted that metformin inhibits complex I of the respiratory chain, altering the ratio of AMP or ADP to ATP and subsequently inhibiting gluconeogenesis [1, 2]. The original insulin clamp… read more here.
Keywords: endogenous glucose; diabetic individuals; metformin; study ... See more keywords
Oral 3‐hydroxybutyrate ingestion decreases endogenous glucose production, lipolysis, and hormone‐sensitive lipase phosphorylation in adipose tissue in men: a human randomized, controlled, crossover trial
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DOI: 10.1111/dme.14385
Abstract: To test whether oral administration of D/L‐3‐hydroxybutyrate as a sodium salt inhibits lipolysis and intracellular lipid signalling, in particular, hormone‐sensitive lipase, and whether D/L‐3‐hydroxybutyrate alters endogenous glucose production. read more here.
Keywords: endogenous glucose; sensitive lipase; hormone sensitive; glucose production ... See more keywords
The effect of small increases in blood glucose on insulin secretion and endogenous glucose production in humans.
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DOI: 10.2337/db24-0388
Abstract: Small glycemic increments (≤0.5 mmol/L) can exert suppressive actions on endogenous glucose production (EGP) however it is unclear if this is an insulin dependent or independent process. Here, we performed a low-rate glucose infusion in… read more here.
Keywords: glucose production; endogenous glucose; insulin secretion; insulin ... See more keywords
1795-LB: Elevation of Endogenous Glucose Production in Persons with Dysglycemia and Impaired Cardiac Function upon Myocardial Infarction
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DOI: 10.2337/db24-1795-lb
Abstract: Introduction & Objective: Prediabetes (PRE) and type 2 diabetes (T2D) associate with excess risk and worse outcome of myocardial infarction (MI). Increased endogenous glucose production (EGP) contributes to hyperglycemia in critical illness, however, if elevated… read more here.
Keywords: none; glucose production; endogenous glucose; myocardial infarction ... See more keywords
A kidney-hypothalamus axis promotes compensatory glucose production in response to glycosuria
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DOI: 10.7554/elife.91540
Abstract: The kidneys facilitate energy conservation through reabsorption of nutrients including glucose. Almost all the filtered blood glucose is reabsorbed by the kidneys. Loss of glucose in urine (glycosuria) is offset by an increase in endogenous… read more here.
Keywords: glycosuria; glucose production; endogenous glucose; axis ... See more keywords