Structural Biology of Human GPCR Drugs and Endogenous Ligands - Insights from NMR Spectroscopy.
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DOI: 10.1016/j.ymeth.2020.08.008
Abstract: G protein-coupled receptors (GPCRs) represent the largest class of "druggable" proteins in the human genome. For more than a decade, crystal structures and, more recently, cryoEM structures of GPCR complexes have provided unprecedented insight into… read more here.
Keywords: endogenous ligands; structural biology; nmr spectroscopy; biology ... See more keywords