Enzyme-Mediated Reactions of Phenolic Pollutants and Endogenous Metabolites as an Overlooked Metabolic Disruption Pathway.
Sign Up to like & getrecommendations! Published in 2022 at "Environmental science & technology"
DOI: 10.1021/acs.est.1c08141
Abstract: It is generally recognized that phenol-containing molecules mainly undergo phase II metabolic reactions, whereas glucuronide and sulfate are conjugated to form water-soluble products. Here, we report direct reactions of phenolic pollutants (triclosan, alkylphenol, bisphenol A… read more here.
Keywords: bpa ves; overlooked metabolic; endogenous metabolites; metabolic disruption ... See more keywords
A synthesis and quantification method for endogenous metabolites dimethylguanidino valeric acid
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-94932-z
Abstract: Dimethylguanidino valeric acid (DMGV) is a group of endogenous metabolites derived from arginine-containing proteins and is associated with several metabolic disorders. Latest studies have identified the stereoisomers of DMGV: asymmetric dimethylguanidino valeric acid (ADGV) and… read more here.
Keywords: method; valeric acid; dmgv; synthesis ... See more keywords
Cytotoxic Profiling of Endogenous Metabolites Relevant to Chronic Fatigue Immune Dysfunction Syndrome (CFIDS) on p53 Variant Human Colon Carcinoma Cell Lines
Sign Up to like & getrecommendations! Published in 2018 at "Dose-Response"
DOI: 10.1177/1559325818790999
Abstract: Chemoprophylatic strategies against development of multifactorial diseases utilize compounds to block the multistep events in chronic inflammation and carcinogenesis. The successful chemopreventative candidate must therefore selectively inhibit growth of transformed cells and be administered frequently… read more here.
Keywords: variant human; cell lines; endogenous metabolites; p53 ... See more keywords