Articles with "endogenous quadruplex" as a keyword



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Endogenous G-quadruplex-forming RNAs inhibit the activity of SARS-CoV-2 RNA polymerase.

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Published in 2023 at "Chemical communications"

DOI: 10.1039/d2cc05858h

Abstract: Replication of RNA viruses is catalysed by virus-specific polymerases, which can be targets of therapeutic strategies. In this study, we used a selection strategy to identify endogenous RNAs from a transcriptome library derived from lung… read more here.

Keywords: quadruplex forming; rna polymerase; activity; endogenous quadruplex ... See more keywords