Harnessing Antibody-Mimetic Selectivity for Activation-State-Specific Targeted Degradation of Endogenous K-Ras
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DOI: 10.1021/acscentsci.1c00084
Abstract: The Ras family of GTPases and are important but poorly druggable therapeutic targets that are frequently mutated in cancer. In this issue of ACS Central Science, Lim et al. present the development of a panel… read more here.
Keywords: state; degradation endogenous; degradation; small molecule ... See more keywords