Identification of a potentially novel LncRNA-miRNA-mRNA competing endogenous RNA network in pulmonary arterial hypertension via integrated bioinformatic analysis.
Sign Up to like & getrecommendations! Published in 2021 at "Life sciences"
DOI: 10.1016/j.lfs.2021.119455
Abstract: AIMS Pulmonary arterial hypertension (PAH) is a fatal cardiovascular disease with a cancer-like phenotype. Competing endogenous RNA (ceRNA) networks extensively involve in its pathological processes. But rare ceRNA networks and profound molecular mechanisms have been… read more here.
Keywords: network; arterial hypertension; analysis; endogenous rna ... See more keywords
DNA Transformer for Visualizing Endogenous RNA Dynamics in Live Cells.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.8b02826
Abstract: The functions of RNA are tightly regulated via diverse intracellular mechanisms. However, probing the complex dynamics of endogenous RNA in live cells is a challenging task. In the present study, a DNA transformer is designed… read more here.
Keywords: endogenous rna; live cells; transformer visualizing; dna transformer ... See more keywords
The long non-coding RNA, SNHG6-003, functions as a competing endogenous RNA to promote the progression of hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2017 at "Oncogene"
DOI: 10.1038/onc.2016.278
Abstract: The expression of long non-coding RNAs (lncRNAs) is dysregulated in hepatocellular carcinoma (HCC). However, the functions and contributions of lncRNAs remain largely unknown. Here, we identified a critical role of SNHG6-003 in HCC. We found… read more here.
Keywords: hepatocellular carcinoma; endogenous rna; long non; non coding ... See more keywords
Role of exosomal competitive endogenous RNA (ceRNA) in diagnosis and treatment of malignant tumors
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2073130
Abstract: ABSTRACT Malignant tumors are a threat to human health, thus it is critical to better understand the mechanism of tumor occurrence and development and to find key therapeutic targets. Competitive endogenous RNA (ceRNA) is a… read more here.
Keywords: competitive endogenous; malignant tumors; cerna diagnosis; rna ... See more keywords
Noncoding RNA-Associated Competing Endogenous RNA Networks in Doxorubicin-Induced Cardiotoxicity.
Sign Up to like & getrecommendations! Published in 2022 at "DNA and cell biology"
DOI: 10.1089/dna.2022.0022
Abstract: Accumulating evidence has indicated that noncoding RNAs (ncRNAs) are involved in doxorubicin-induced cardiotoxicity (DIC). However, the ncRNA-associated competing endogenous RNA (ceRNA)-mediated regulatory mechanisms in DIC remain unclear. In this study, we aimed to systematically investigate… read more here.
Keywords: induced cardiotoxicity; rna; competing endogenous; associated competing ... See more keywords
Competing endogenous RNA network in newly diagnosed multiple myeloma by genetic microarray
Sign Up to like & getrecommendations! Published in 2020 at "Chinese Medical Journal"
DOI: 10.1097/cm9.0000000000001108
Abstract: Multiple myeloma (MM) is a blood malignancy characterized by the clonal proliferation of plasma cells, which increases the number of monoclonal immunoglobulins in blood and urine and causes target organ damage. Long non-coding RNAs (lncRNAs)… read more here.
Keywords: rna network; endogenous rna; multiple myeloma; competing endogenous ... See more keywords
Competing endogenous RNA network construction based on long non-coding RNAs, microRNAs, and mRNAs related to fat deposition in Songliao black swine.
Sign Up to like & getrecommendations! Published in 2023 at "Animal genetics"
DOI: 10.1111/age.13283
Abstract: China has a long history of pig breeding and a number of local breeds. The Songliao Black pig, bred in China in 2009, shows high variation in backfat thickness and therefore is well-suited to fat… read more here.
Keywords: rna; fat deposition; deposition; competing endogenous ... See more keywords
Differential Expression Profiles of mRNA and Noncoding RNA and Analysis of Competitive Endogenous RNA Regulatory Networks in Nonalcoholic Steatohepatitis
Sign Up to like & getrecommendations! Published in 2022 at "Gastroenterology Research and Practice"
DOI: 10.1155/2022/3200932
Abstract: Nonalcoholic steatohepatitis (NASH) is a liver disease caused by multiple factors, and there is no approved pharmacotherapy. The pathogenesis of NASH remains underexplored. In this study, differentially expressed circular RNAs (circRNAs) were obtained by analyzing… read more here.
Keywords: profiles mrna; endogenous rna; expression profiles; rna ... See more keywords
Integrated analysis of competing endogenous RNA network revealing lncRNAs as potential prognostic biomarkers in human lung squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.19627
Abstract: Accumulating evidence shows the important role of long non-coding RNAs (lncRNAs) in competing endogenous RNA (ceRNA) networks for predicting survival in tumor patients. However, prognostic biomarkers for lung squamous cell carcinoma (LUSC) are still lacking.… read more here.
Keywords: network; lusc patients; endogenous rna; rna ... See more keywords
An in-silico Approach for Recognition of Long non-coding RNA-Associated Competing Endogenous RNA Axes in Prostate Cancer.
Sign Up to like & getrecommendations! Published in 2023 at "Urology journal"
DOI: 10.22037/uj.v20i.7650
Abstract: Prostate cancer is among the most central sources of cancer-related mortalities. In order to find novel candidates for therapeutic strategies in this kind of cancer, we developed an in-silico method for identification of competing endogenous… read more here.
Keywords: prostate cancer; rna; silico approach; competing endogenous ... See more keywords
The Construction and Analysis of lncRNA–miRNA–mRNA Competing Endogenous RNA Network of Schwann Cells in Diabetic Peripheral Neuropathy
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2020.00490
Abstract: Background Diabetes mellitus is a worldwide disease with high incidence. Diabetic peripheral neuropathy (DPN) is one of the most common but often ignored complications of diabetes mellitus that cause numbness and pain, even paralysis. Recent… read more here.
Keywords: network; endogenous rna; dpn; diabetic peripheral ... See more keywords