Dissection of functional lncRNAs in Alzheimer's disease by construction and analysis of lncRNA-mRNA networks based on competitive endogenous RNAs.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2016.11.143
Abstract: Alzheimer's disease (AD) is a neurodegenerative disorder that is the most common cause of dementia in the elderly, and intracellular neurofibrillary tangles (NFTs) are one of the pathological features of AD. Recent studies have suggested… read more here.
Keywords: alzheimer disease; analysis; endogenous rnas; lncrna mrna ... See more keywords
MicroRNAs and ‘Sponging’ Competitive Endogenous RNAs Dysregulated in Colorectal Cancer: Potential as Noninvasive Biomarkers and Therapeutic Targets
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DOI: 10.3390/ijms23042166
Abstract: The gastrointestinal (GI) tract in mammals is comprised of dozens of cell types with varied functions, structures, and histological locations that respond in a myriad of ways to epigenetic and genetic factors, environmental cues, diet,… read more here.
Keywords: competitive endogenous; sponging competitive; micrornas sponging; colorectal cancer ... See more keywords
Regulation of the Key Epithelial Cancer Suppressor miR-124 Function by Competing Endogenous RNAs
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DOI: 10.3390/ijms232113620
Abstract: A decrease in the miR-124 expression was observed in various epithelial cancers. Like a classical suppressor, miR-124 can inhibit the translation of multiple oncogenic proteins. Epigenetic mechanisms play a significant role in the regulation of… read more here.
Keywords: mir 124; competing endogenous; regulation; suppressor mir ... See more keywords