Human endoglin as a potential new partner involved in platelet–endothelium interactions
Sign Up to like & getrecommendations! Published in 2017 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-017-2694-7
Abstract: Complex interactions between platelets and activated endothelium occur during the thrombo-inflammatory reaction at sites of vascular injuries and during vascular hemostasis. The endothelial receptor endoglin is involved in inflammation through integrin-mediated leukocyte adhesion and transmigration;… read more here.
Keywords: endothelium; human endoglin; adhesion; endothelial cells ... See more keywords
Can serum endoglin be used to improve the diagnostic performance in prostate cancer?
Sign Up to like & getrecommendations! Published in 2021 at "World Journal of Urology"
DOI: 10.1007/s00345-021-03714-5
Abstract: New biomarkers may contribute to avoid unnecessary biopsies resulting from the suboptimal performance of prostate-specific antigen (PSA) testing. This study aimed to assess serum endoglin as a prostate cancer (PCa) diagnostic tool among biopsy candidates.… read more here.
Keywords: cancer; performance prostate; endoglin; serum endoglin ... See more keywords
Circulating s-Endoglin concentrations in non-obese patients with gestational diabetes mellitus
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Obstetrics and Gynaecology"
DOI: 10.1080/01443615.2021.2012436
Abstract: Abstract The aim of this study was to compare maternal concentrations of soluble Endodlin (s-Endoglin) in women with gestational diabetes (GDM) and women with normal glucose tolerance (NGT) in pregnancy. Also, the association of insulin… read more here.
Keywords: concentrations non; non obese; endoglin; circulating endoglin ... See more keywords
Endoglin Mediates Vascular Maturation by Promoting Vascular Smooth Muscle Cell Migration and Spreading
Sign Up to like & getrecommendations! Published in 2017 at "Arteriosclerosis, Thrombosis, and Vascular Biology"
DOI: 10.1161/atvbaha.116.308859
Abstract: Objective— Endoglin, a transforming growth factor-&bgr; superfamily coreceptor, is predominantly expressed in endothelial cells and has essential roles in vascular development. However, whether endoglin is also expressed in vascular smooth muscle cells (VSMCs), especially in… read more here.
Keywords: vsmcs; vascular smooth; biology; endothelial cells ... See more keywords
Negative correlation between endoglin levels and coronary atherosclerosis
Sign Up to like & getrecommendations! Published in 2021 at "Lipids in Health and Disease"
DOI: 10.1186/s12944-021-01545-2
Abstract: Background Coronary artery disease (CAD) is a common cardiovascular disease, and abnormal blood lipid metabolism is an important risk factor. Transforming growth factor-ß (TGF-ß) and its receptor (TGF-ßR) can inhibit the release of inflammatory factors… read more here.
Keywords: endoglin; coronary atherosclerosis; tgf; endothelial cells ... See more keywords
Increased soluble endoglin levels in newly-diagnosed type 2 diabetic patients are associated with endothelial dysfunction.
Sign Up to like & getrecommendations! Published in 2023 at "Endocrine journal"
DOI: 10.1507/endocrj.ej22-0550
Abstract: Endothelial dysfunction (ED) contributes to the pathologic process underlying macrovascular complications, a common complication of type 2 diabetes mellitus (T2DM). Soluble endoglin (sEng) shed from the extracellular domain of the entire endoglin molecule blocks endothelial… read more here.
Keywords: serum seng; endoglin; seng level; newly diagnosed ... See more keywords
The relation of serum endocan and soluble endoglin levels with metabolic control in children and adolescents with type 1 diabetes mellitus
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Pediatric Endocrinology and Metabolism"
DOI: 10.1515/jpem-2020-0146
Abstract: Abstract Objectives Endothelial dysfunction is an early marker of vascular disease in Type 1 diabetes mellitus (T1DM). In the present study, we aimed to investigate serum endocan and soluble endoglin (S-endoglin) levels, and their relation… read more here.
Keywords: serum endocan; metabolic control; endoglin levels; endoglin ... See more keywords
Expression Profile of Endoglin in Different Grades of Endometrial Cancer.
Sign Up to like & getrecommendations! Published in 2018 at "Current pharmaceutical biotechnology"
DOI: 10.2174/1389201020666181127152605
Abstract: BACKGROUND Endoglin is a marker of active, proliferating endothelial cells of blood vessels. In many cancers, it is present in both peripheral vessels and vessels located inside the tumor. Endoglin is more specific and sensitive… read more here.
Keywords: expression profile; marker; endometrial cancer; cancer ... See more keywords
MMP-14 aggravates onset of severe preeclampsia by mediating soluble endoglin release.
Sign Up to like & getrecommendations! Published in 2018 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_201803_14460
Abstract: OBJECTIVE Gestational hypertension is a pregnancy complication that serious damages the maternal and child health. Early onset severe preeclampsia accounts for about 0.9% of the gestational hypertension disease. Conservative treatment is proposed in recent years… read more here.
Keywords: onset severe; mmp; preeclampsia; severe preeclampsia ... See more keywords
Endoglin: An ‘Accessory’ Receptor Regulating Blood Cell Development and Inflammation
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21239247
Abstract: Transforming growth factor-β1 (TGF-β1) is a pleiotropic factor sensed by most cells. It regulates a broad spectrum of cellular responses including hematopoiesis. In order to process TGF-β1-responses in time and space in an appropriate manner,… read more here.
Keywords: accessory receptor; inflammation; receptor; factor ... See more keywords
Regulation and Release of Vasoactive Endoglin by Brain Endothelium in Response to Hypoxia/Reoxygenation in Stroke
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23137085
Abstract: In large vessel occlusion stroke, recanalization to restore cerebral perfusion is essential but not necessarily sufficient for a favorable outcome. Paradoxically, in some patients, reperfusion carries the risk of increased tissue damage and cerebral hemorrhage.… read more here.
Keywords: reoxygenation; endoglin; brain; expression ... See more keywords