Articles with "endolysosome autolysosome" as a keyword



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Endolysosome and Autolysosome Dysfunction in Alzheimer’s Disease: Where Intracellular and Extracellular Meet

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Published in 2019 at "CNS Drugs"

DOI: 10.1007/s40263-019-00643-1

Abstract: Disturbed proteostasis as reflected by a massive accumulation of misfolded protein aggregates is a central feature in Alzheimer’s disease. Proteostatic disturbances may be caused by a shift in protein production and clearance. Whereas rare genetic… read more here.

Keywords: endolysosome autolysosome; alzheimer disease; dysfunction; disease ... See more keywords