Establishment of a nine‐gene prognostic model for predicting overall survival of patients with endometrial carcinoma
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DOI: 10.1002/cam4.1498
Abstract: Endometrial carcinoma (EC) is the most common malignant tumor of the female genital tract in developed countries. The prognosis of early stage EC is favorable, but a subset faces high risk of cancer progression or… read more here.
Keywords: risk; model predicting; predicting overall; prognostic model ... See more keywords
DACH1 suppresses epithelial to mesenchymal transition (EMT) through Notch1 pathway and reverses progestin resistance in endometrial carcinoma
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DOI: 10.1002/cam4.2317
Abstract: Progestin resistance limits the effectiveness of progestin therapy in endometrial carcinoma for patients who desire to preserve fertility. To investigate the molecular mechanism of progestin resistance in endometrial carcinoma, we performed microarray analysis among Ishikawa… read more here.
Keywords: dach1; progestin resistance; endometrial carcinoma; resistance ... See more keywords
FAT2 mutation is associated with better prognosis and responsiveness to immunotherapy in uterine corpus endometrial carcinoma
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DOI: 10.1002/cam4.5119
Abstract: Uterine corpus endometrial carcinoma (UCEC) ranks sixth among malignant tumors in women and the mortality is still rising. FAT2 gene has been considered to be related to the survival and prognosis of some certain diseases… read more here.
Keywords: endometrial carcinoma; prognosis; uterine corpus; prognosis responsiveness ... See more keywords
Endometrial carcinoma recurrence according to race and ethnicity: An NRG Oncology/Gynecologic Oncology Group 210 Study
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DOI: 10.1002/ijc.31127
Abstract: Non‐Hispanic black (NHB) women are more likely to experience an endometrial carcinoma (EC) recurrence compared to non‐Hispanic white (NHW) women. The extent to which tumor characteristics, socioeconomic status (SES) and treatment contribute to this observation… read more here.
Keywords: race ethnicity; oncology; endometrial carcinoma; recurrence ... See more keywords
Circ_0109046 promotes the malignancy of endometrial carcinoma cells through the microRNA‐105/SOX9/Wnt/β‐catenin axis
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DOI: 10.1002/iub.2415
Abstract: Emerging evidence suggests the important involvements of circular RNAs (circRNAs) in cancer progression. This study focuses on the function of Circ_0109046 on the malignancy of endometrial carcinoma (EC) cells and the molecules involved. First, high… read more here.
Keywords: wnt catenin; endometrial carcinoma; malignancy endometrial; circ 0109046 ... See more keywords
MicroRNA‐424 regulates epithelial‐mesenchymal transition of endometrial carcinoma by directly targeting insulin‐like growth factor 1 receptor
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27528
Abstract: Although numerous miRNAs are reported to contribute to the carcinogenesis of malignant tumor, the specific role of miR‐424 in endometrial carcinoma is seldom reported. To explore the effect of miR‐424 on epithelial‐mesenchymal transition and its… read more here.
Keywords: factor; mir 424; endometrial carcinoma; transition ... See more keywords
Six‐transmembrane epithelial antigen of the prostate 1 is associated with tumor invasion and migration in endometrial carcinomas
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DOI: 10.1002/jcb.28393
Abstract: Six‐transmembrane epithelial antigen of the prostate 1 (STEAP1), a member of the STEAP family, is a general tumor antigen. However, no information has been available to date regarding the function of STEAP1 in the progression… read more here.
Keywords: invasion; steap1; migration; endometrial carcinoma ... See more keywords
Identifying prognostic biomarkers in endometrial carcinoma based on ceRNA network
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DOI: 10.1002/jcb.29466
Abstract: Endometrial carcinoma (EC), a common gynecological malignancy with high incidence, affects the mental and physical health of women. Mounting evidence shows that long noncoding RNAs (lncRNAs), messenger RNAs (mRNAs), and microRNAs (miRNAs) have instrumental roles… read more here.
Keywords: carcinoma; carcinoma based; prognostic biomarkers; endometrial carcinoma ... See more keywords
High expression of the ferroptosis‐associated MGST1 gene in relation to poor outcome and maladjusted immune cell infiltration in uterine corpus endometrial carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24317
Abstract: Uterine corpus endometrial carcinoma (UCEC) tightly correlates with dysregulated iron homeostasis. MGST1 (microsomal glutathione S‐transferase 1) involves in the regulation of oxidative stress and plays a key role in inhibiting iron‐mediated cell death in cancer… read more here.
Keywords: corpus endometrial; cell; endometrial carcinoma; uterine corpus ... See more keywords
Aberrant TRPC1 expression reflects stromal cervical invasion, lymphovascular invasion, elevated FIGO stage, and poor survival in resectable endometrial carcinoma patients
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24560
Abstract: Transient receptor potential channel 1 (TRPC1) promotes tumor growth and metastasis in endometrial carcinoma (EC) cell lines, whereas its clinical role in EC management remains unclear. Therefore, this study aimed to investigate the association of… read more here.
Keywords: endometrial carcinoma; trpc1 expression; invasion; aberrant trpc1 ... See more keywords
GLP1R inhibits the progression of endometrial carcinoma through activation of cAMP/PKA pathway
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DOI: 10.1002/jcla.24604
Abstract: This study strived to explore the role and mechanism of glucagon‐like peptide‐1 receptor (GLP1R) in endometrial carcinoma (EC). read more here.
Keywords: inhibits progression; endometrial carcinoma; progression endometrial; glp1r inhibits ... See more keywords