A Comparative Analysis of Immunohistochemical Profile of Primary and Metastatic Endometrial Endometrioid Carcinoma
Sign Up to like & getrecommendations! Published in 2020 at "American Journal of Clinical Pathology"
DOI: 10.1093/ajcp/aqaa161.066
Abstract: Beta catenin plays an important role in cancer tumorigenesis and have been found to be associated with metastasis in a variety of tumors. Analyzing TCGA data, we found that 30% of endometrial endometrioid carcinoma cases… read more here.
Keywords: carcinoma; endometrioid carcinoma; beta catenin; primary metastatic ... See more keywords
Microcystic, elongated and fragmented (MELF) pattern in endometrial carcinoma: clinicopathologic analysis and prognostic implications
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DOI: 10.1097/md.0000000000031369
Abstract: To assess the clinical value of microcystic, elongated, and fragmented (MELF) pattern in Chinese patients with endometrial endometrioid carcinoma. A total of 189 patients with endometrial endometrioid carcinoma were retrospectively analyzed in Peking University Third… read more here.
Keywords: microcystic elongated; elongated fragmented; melf pattern; endometrial endometrioid ... See more keywords
Endometrial Endometrioid Carcinoma With Ovarian Metastasis Showing Morula-like Features in a Patient With Cowden Syndrome: A Case Report.
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Gynecological Pathology"
DOI: 10.1097/pgp.0000000000000576
Abstract: Cowden syndrome (CS) is a multiple hamartoma syndrome associated with the development of various tumors, including endometrial cancer. However, the histology of CS-associated endometrial cancer remains to be fully described. To our knowledge, this is… read more here.
Keywords: ovarian metastasis; endometrioid carcinoma; histology; endometrial endometrioid ... See more keywords
Clinicopathologic and Immunohistochemical Correlates of CTNNB1 Mutated Endometrial Endometrioid Carcinoma
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DOI: 10.1097/pgp.0000000000000583
Abstract: Endometrial endometrioid carcinomas (EECs) with exon 3 CTNNB1 mutations characterize a more aggressive subset of tumors in patients with low-grade low-stage disease. Thus, prospectively identifying these cases may be clinically relevant. The aim of this… read more here.
Keywords: catenin; ctnnb1 mutated; endometrial endometrioid; ctnnb1 ... See more keywords
Clinicopathologic Evaluation and Molecular Profiling of Recurrent Stage IA Endometrial Endometrioid Carcinoma: A Case-control Study
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DOI: 10.1097/pgp.0000000000000856
Abstract: Most low-grade, early-stage endometrial endometrioid carcinomas (EEC) have an excellent prognosis; however, recurrences occur in a small subset with several studies reporting an increase in CTNNB1 exon 3 mutations in this population. Herein we evaluated… read more here.
Keywords: endometrial endometrioid; eecs; stage; study ... See more keywords
Clinicopathologic Evaluation of CTNNB1 Mutations in High-Intermediate Risk Endometrial Endometrioid Carcinoma
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DOI: 10.1097/pgp.0000000000000865
Abstract: CTNNB1 mutations convey increased risk of recurrence in low-risk endometrial endometrioid carcinoma (EEC). Results from previous high-intermediate risk (HIR) cohorts are mixed. The aims of this study were to correlate CTNNB1 mutational status with clinical… read more here.
Keywords: endometrial endometrioid; recurrence; risk; risk endometrial ... See more keywords
Role of adjuvant chemotherapy in patients with FIGO stage IB grade 3 endometrial endometrioid adenocarcinoma treated with surgery and post-operative radiotherapy
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DOI: 10.1136/ijgc-2021-002380
Abstract: Background The optimal treatment of patients with FIGO stage IB grade 3 endometrial endometrioid adenocarcinoma remains unknown. Objective To compare overall survival following treatment with a hysterectomy and adjuvant radiotherapy with or without chemotherapy in… read more here.
Keywords: chemotherapy; stage grade; figo stage; endometrioid adenocarcinoma ... See more keywords
Downregulation of tyrosine threonine kinase inhibits tumor growth via G2/M arrest in human endometrioid endometrial adenocarcinoma
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DOI: 10.1177/1010428317712444
Abstract: Endometrial cancer is the most common gynecologic malignancy, about 80% of which is endometrial endometrioid carcinoma. Dysregulation of spindle assembly checkpoint plays a vital role in endometrial endometrioid carcinoma tumorigenesis and progression. The purpose of… read more here.
Keywords: endometrial endometrioid; endometrioid carcinoma; threonine kinase; tyrosine threonine ... See more keywords