Screening and surgical prophylaxis for hereditary cancer syndromes with high risk of endometrial and ovarian cancer
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Surgical Oncology"
DOI: 10.1002/jso.25645
Abstract: In the era of advanced cancer genomics, our recognition of hereditary cancer mutations continues to increase. Two of these conditions, which carry an increased risk of female cancers including endometrial, ovarian, breast, are hereditary breast… read more here.
Keywords: risk; hereditary cancer; endometrial ovarian; ovarian cancer ... See more keywords
Cytochrome P450 3A4, 3A5, and 2C8 expression in breast, prostate, lung, endometrial, and ovarian tumors: relevance for resistance to taxanes
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Chemotherapy and Pharmacology"
DOI: 10.1007/s00280-019-03905-3
Abstract: Enzymes of the cytochrome P450 (CYP) subfamily 3A and 2C play a major role in the metabolism of taxane anticancer agents. While their function in hepatic metabolism of taxanes is well established, expression of these… read more here.
Keywords: ovarian tumors; lung endometrial; endometrial ovarian; expression ... See more keywords
Management of endometrial, ovarian and cervical cancer in the elderly: current approach to a challenging condition
Sign Up to like & getrecommendations! Published in 2018 at "Archives of Gynecology and Obstetrics"
DOI: 10.1007/s00404-018-5006-z
Abstract: AbstractPurposeGynaecological cancer management in older people represents a current challenge. Therefore, in the present paper, we aimed to gather all the evidence reported in the literature concerning gynecological cancers in the elderly, illustrating the state… read more here.
Keywords: management endometrial; gynecological cancers; endometrial ovarian; cervical cancer ... See more keywords
Sugar-containing beverages and their association with risk of breast, endometrial, ovarian and colorectal cancers among Canadian women.
Sign Up to like & getrecommendations! Published in 2020 at "Cancer epidemiology"
DOI: 10.1016/j.canep.2020.101855
Abstract: BACKGROUND The association of sugar containing beverages (SCBs) with risk of breast, endometrial, ovarian and colorectal cancers is unclear. Therefore, we investigated these associations in the Canadian Study of Diet, Lifestyle, and Health. METHODS The… read more here.
Keywords: risk; breast endometrial; endometrial ovarian; ovarian colorectal ... See more keywords
Nut and peanut butter intake are not directly associated with the risk of endometrial or ovarian cancer: Results from a Dutch prospective cohort study.
Sign Up to like & getrecommendations! Published in 2019 at "Clinical nutrition"
DOI: 10.1016/j.clnu.2019.09.008
Abstract: BACKGROUND & AIMS Nut intake has been associated with reduced cancer-related mortality and cancer risk. However, very few studies investigated the association between nut consumption and the risk of endometrial and ovarian cancer, with inconclusive… read more here.
Keywords: risk endometrial; endometrial ovarian; peanut; ovarian cancer ... See more keywords
An analysis of the association between statin use and risk of endometrial and ovarian cancers in the Women's Health Initiative.
Sign Up to like & getrecommendations! Published in 2018 at "Gynecologic oncology"
DOI: 10.1016/j.ygyno.2018.01.006
Abstract: BACKGROUND Statins have anti proliferative activity in vitro against endometrial and ovarian cancer and can affect levels of reproductive hormones. We analyzed data from the Women's Health Initiative (WHI) to assess whether statins are associated… read more here.
Keywords: risk endometrial; risk; endometrial ovarian; statin ... See more keywords
Associations of a Healthy Lifestyle Index With the Risks of Endometrial and Ovarian Cancer Among Women in the Women’s Health Initiative Study
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Epidemiology"
DOI: 10.1093/aje/kwy249
Abstract: Lifestyle-related factors influence risk of endometrial and ovarian cancers, but few studies have examined their joint associations with risk of these cancers. Using multivariable Cox regression models, we assessed the association of a healthy lifestyle… read more here.
Keywords: risk; healthy lifestyle; index; endometrial ovarian ... See more keywords
EP554 The effects of Cimicifuga racemosa extract on endometrial and ovarian cancer cell lines
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Gynecological Cancer"
DOI: 10.1136/ijgc-2019-esgo.611
Abstract: Introduction/Background In postmenopausal women estrogen levels depend solely upon the local formation from steroid precursors, dehydroepiandrosterone-sulfate and estrone-sulfate (E1-S). Decreased estrogen levels are associated with menopausal symptoms, which often occur in peri- and postmenopausal women.… read more here.
Keywords: ovarian cancer; cancer; endometrial ovarian; cimicifuga racemosa ... See more keywords
Abstract CT035: A phase Ib study of miransertib (ARQ 092) in combination with anastrozole in patients with PIK3CA or AKT1-mutant ER+ endometrial or ovarian cancer
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-ct035
Abstract: Background: Activating PI3K pathway mutations are common in endometrial and a subset of non-serous ovarian cancers and are frequently found in tumors that co-express the estrogen receptor (ER). We evaluated the safety and preliminary efficacy… read more here.
Keywords: combination; endometrial ovarian; pik3ca akt1; ovarian cancer ... See more keywords
Longitudinal assessment of post-surgical physical activity in endometrial and ovarian cancer patients
Sign Up to like & getrecommendations! Published in 2019 at "PLoS ONE"
DOI: 10.1371/journal.pone.0223791
Abstract: Objective Physical activity plays a key role in cancer survivorship. The purpose of this investigation was to (a) describe the post-surgical physical activity trajectories of endometrial (n = 65) and ovarian (n = 31) cancer… read more here.
Keywords: endometrial ovarian; ovarian cancer; post; physical activity ... See more keywords
Physiological Concentrations of Cimicifuga racemosa Extract Do Not Affect Expression of Genes Involved in Estrogen Biosynthesis and Action in Endometrial and Ovarian Cell Lines
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12040545
Abstract: In postmenopausal women, estrogen levels exclusively depend on local formation from the steroid precursors dehydroepiandrosterone sulfate and estrone sulfate (E1-S). Reduced estrogen levels are associated with menopausal symptoms. To mitigate these symptoms, more women nowadays… read more here.
Keywords: cimicifuga racemosa; ovarian cell; endometrial ovarian; cell lines ... See more keywords